Disease: Lupus Erythematosus, Systemic
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs12720356
TYK2
0.752 0.360 19 10359299 missense variant A/C;G snv 6.1E-02; 4.0E-06 12
rs1801274
FCGR2A
0.597 0.800 1 161509955 missense variant A/C;G snv 4.0E-06; 0.48 46
rs1805087
MTR
0.496 0.800 1 236885200 missense variant A/G snv 0.20 0.21 135
rs1805192
PPARG
0.510 0.840 3 12379739 missense variant C/G snv 121
rs1990760
IFIH1
0.672 0.480 2 162267541 missense variant C/T snv 0.50 0.45 33
rs2032582
ABCB1
0.538 0.800 7 87531302 missense variant A/C;T snv 0.54; 3.8E-02 97
rs2476601
AP4B1-AS1 ; PTPN22
0.498 0.800 1 113834946 missense variant A/G snv 0.93 0.93 121
rs34536443
TYK2
0.667 0.400 19 10352442 missense variant G/C snv 2.7E-02 2.8E-02 25
rs35018800
TYK2
0.790 0.160 19 10354167 missense variant G/A snv 4.6E-03 4.9E-03 9
rs4246905
TNFSF15
0.716 0.400 9 114790969 missense variant T/A;C snv 0.76 16
rs4986790
TLR4
0.438 0.800 9 117713024 missense variant A/G;T snv 6.1E-02; 4.0E-06 223
rs4986791
TLR4
0.456 0.840 9 117713324 missense variant C/T snv 5.7E-02 4.9E-02 182
rs5029941
TNFAIP3
1.000 0.080 6 137874923 missense variant C/T snv 1.2E-03 5.6E-03 2
rs5743708
TLR2
0.525 0.800 4 153705165 missense variant G/A snv 1.7E-02 1.8E-02 98
rs721917
SFTPD
0.752 0.360 10 79946568 missense variant A/G snv 0.47 0.42 14
rs763780
IL17F
0.531 0.720 6 52236941 missense variant T/C snv 6.7E-02 6.6E-02 87
rs878859113
CD24
0.763 0.360 6 106971734 missense variant G/A snv 0.35 11
rs2111485 0.724 0.280 2 162254026 regulatory region variant A/G snv 0.46 17
rs9271366 0.807 0.240 6 32619077 intergenic variant G/A snv 0.86 9
rs1457092
MYO9B
0.790 0.320 19 17193427 intron variant C/A snv 0.44 8
rs1517352
STAT4
0.851 0.160 2 191066738 intron variant A/C snv 0.45 5
rs1800896
IL19 ; IL10
0.507 0.800 1 206773552 intron variant T/C snv 0.41 113
rs2187668
LOC107986589 ; HLA-DQA2 ; HLA-DQA1
0.701 0.480 6 32638107 intron variant C/T snv 3.3E-03 20
rs2430561
IFNG ; IFNG-AS1
0.590 0.760 12 68158742 intron variant T/A snv 0.36 50
rs3024493
IL19 ; IL10
0.776 0.280 1 206770623 intron variant C/A;T snv 0.11 9